A novel therapeutic approach, clinically proven to be safe and effective

Combined Optical and Magnetic Stimulation for promotion of wound healing

The COMS One therapy system is intended to promote wound healing in chronic leg and foot ulcers, in addition to standard of care. The device is locally applied to the wound area for 16 min, 2-3 times per week, over a recommended duration of 6-8 weeks.

  • Non-invasive, safe, effective
  • Lightweight & portable
  • Intuitive handling, minimal training effort
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Chronic wounds

Driven by diabetes and the effects of an ageing population, hard-to-heal wounds remain a major challenge for modern healthcare systems.

Chronic cutaneous ulcers are defined as wounds which fail to proceed through phases of wound healing in an orderly and timely manner to produce a durable structural functional and cosmetic closure. Macro and microvascular disorders are some of the most frequent causes for a delayed wound healing process.

Ulcus Cruris

Ulcus Cruris

About 1% of population suffers from venous ulcers, arterial ulcers or mixed ulcers. Source.
Diabetic Foot Ulcer

Diabetic Foot Ulcer

Diabetic foot ulcers are a common complication of diabetes and affect approximately up to 25% of the diabetic population. Source.

Mechanism of Action

Advanced wound care through combined optical and magnetic stimulation

Optical stimulation

Optical stimulation

Photobiomodulation is a non-thermal process which involves endogenous light absorbing molecules that elicit photo-physical events at biological scale. Light in the far red to near infrared spectral range using low energy light emitting sources is reported to be especially bio-modulative. Triggering phase transitions in the active centre of Cytochrome C oxidase, facilitates the substrate to product conversion and augments the turnover rates of the enzyme. A kick-start for cellular respiration. Photobiomodulation has now accumulated evidence of a positive action on all phases of wound repair from the first inflammatory phases to the remodelling phase. Source.

Magnetic stimulation

Magnetic stimulation

"In healthy tissue, the body's endogenous electric fields guide the wound healing processes. In chronic wound situations, where the surrounding tissue is poorly perfused, such endogenous electric currents are found to be reduced. Via time varying magnetic fields, small electric currents can be induced in biological tissue. Feigning these endogenous electric currents in a chronic wound situation is promising to restore tissue integrity and promote wound healing.“Magnetic fields have been associated with an intense anti-inflammatory action, mediated by the shift in the production of cytokines from a pro-inflammatory pattern to an anti-inflammatory pattern. This can speed up the movement from the chronic inflammatory phase, which is typical for chronic wounds, to a more pro-reparative phase of tissue repair.“ Source.

COMS® Technology

The COMS One therapy system incorporates the technologies for optical and magnetic stimulation. The optical stimulation component of the COMS One Therapy System is designed to emit light by two types of LEDs in the wavelength of 660 nm (red) and 830 nm (near infrared) range of the electromagnetic spectra. The magnetic stimulation component is generated by a coil emitting pulse modulated magnetic fields in the extremely low frequency (ELF) range of the electromagnetic spectra.


Clinical Investigations

Piomic is conducting clinical research to investigate the safety and efficacy of combined optical and magnetic stimulation in chronic foot and leg ulcers. Ongoing clinical investigations include a multicentric clinical trial in Switzerland in the outpatient setting. Future clinical trials in the US will focus on the application in diabetic foot ulcers in a homecare setting/in both outpatient and homecare setting.

Further information on our clinical trial
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